Quote Originally Posted by verminaard View Post
Quote Originally Posted by Daly View Post


I don’t claim to understand the science but I trust some folks that I k is that do. This shit is doing things for patients with Rona that Gilead wishes it’s drug did and with zero side effects. This has a shot to go to the moon, like 1.5B company to 50B.

It’s a gamble - like go to the roulette wheel gamble as is all biotech.. want to be clear about that..... but if you got 4000 in chips in your portfolio this might be worth a shot.
I don't see it. The narrative is that the drug is a CCR5 antagonist that blocks HIV from entering cells, and doesn't have serious side effects and can be used with other therapies.

If this was true this drug would be a VERY big deal in the HIV world. Most HIV-1 strains need to bind to the CCR5 receptor in CD4 T cells in order to establish infection, although they can later mutate inside the host so they don't need do. In fact, the only natural immunity ever observed to HIV is a very rare mutation to CCR5.

This drug has been languishing in trials for 10+ years. If it lived up to the narrative it should be front line HIV therapy. Something isn't adding up.

As far as trials with COVID-19 go, CCR5 is an important chemokine receptor involved in the immune response. So it appears the company is just trying out this drug as a general immune suppressant, as runaway immune response seems to be involved in pathology of serious COVID disease. But there are a lot of immune suppressant drugs, so I don't see why this one would be especially effective.

I wish you good luck with your gambool. But I just don't see it. I would guess this is a pump and dump scheme.

Edit: I just read today's press clippings from today and I guess the company is implying they have discovered a novel reason a CCR5 antagonist would effect SARS-COV2 directly. To date there is no proposed reason a CCR5 antagonist would directly effect the disease process that I know of. FWIW, CCR5 is expressed mainly on immune cells, which are not even cells that SARS-COV2 infects primarily, so I don't have a clue what mechanism they are claiming to have discovered. So I guess we will have to just wait and see what they have to say.
I think in the days and weeks to come you going to hear about how this blocks the cytokine storm from happening as it relates to Convid 19. They are giving it to folks who are deaths doorstep and they are coming off ventilators 2 days later.

Like I said it’s a gamble, not just for my pocketbook but if this holds true it’s big for society.