So coronavirus is definitely going to kill a few of us.

[sonatine]

oh wow weird another pfa thread where casual discussion of how to pragmatically navigate a grid interruption turns into OMG YOU SHOULD THIS GUN BUT NOT THIS GUN

[Gordman]

[SPIT this]

oh wow weird another pfa thread where casual discussion of how to pragmatically navigate a grid interruption turns into OMG YOU SHOULD THIS GUN BUT NOT THIS GUN

Buddy you started a thread about an incoming zombie-virus invasion. Which gun to buy is a pragmatic discussion

[BCR]

Cases 69044
Deaths 1666

[GrenadaRoger]

oh wow weird another pfa thread where casual discussion of how to pragmatically navigate a grid interruption turns into OMG YOU SHOULD THIS GUN BUT NOT THIS GUN

I was ready to dismiss this thread as a load of hysteria until I stopped in my pharmacy to pick up my cholesterol meds...while there I looked for anti-viral face masks--the store was out AND it was the only first aid product (such as band aids, gauze rolls, wraps) not on the shelves. So I went to a couple more that day...same story. A couple days later, visited the same stores plus a few more--same story yet again. Mind you, there are hardly any Asian living in my town, the nearest international airport is over 300 miles away and its a semi-rural, small town area i'm in now.

So, all joking aside, better to be a little prepared...and being in a rural area, public safety and medical services can easily get overwhelmed--best to provide some staying power if things destabilize for a time

lastly re: firearm--imho pick one that is reliable and you can manage...for most people a dual action .22 revolver is better than the best baseball bat, long knife or trick semi-auto they can't maintain.

[MumblesBadly]

oh wow weird another pfa thread where casual discussion of how to pragmatically navigate a grid interruption turns into OMG YOU SHOULD THIS GUN BUT NOT THIS GUN

Buddy you started a thread about an incoming zombie-virus invasion. Which gun to buy is a pragmatic discussion

And I thought the purpose of this thread was to share ideas on how best to profit from this crisis from the safety of our respective hermetically sealed bunkers.

 

[sonatine]

so we are seeing a phase change in the infection model, according to available data.

total daily infections are down, but the overwhelming majority of those new infections were in quarantined burn zones in china, so its possible that telling everyone to stay in their homes and not touch anything ever and if they die they die, is having the desired effect.

unfortunately what we are seeing are 'embers' popping up everywhere. isolated incidents of new infections among people who were suspect but cleared are happening. one in europe, another who just got back from a vacation in hawaii, etc.

so although our vertical infection rate looks like its peaked, each one of these lateral infections can generate more vertical growth.

so unless we get very lucky, we are going to need a vaccine or at least a breakthrough treatment cocktail to put this behind us.

[Gordman]

so we are seeing a phase change in the infection model, according to available data.

total daily infections are down, but the overwhelming majority of those new infections were in quarantined burn zones in china, so its possible that telling everyone to stay in their homes and not touch anything ever and if they die they die, is having the desired effect.

unfortunately what we are seeing are 'embers' popping up everywhere. isolated incidents of new infections among people who were suspect but cleared are happening. one in europe, another who just got back from a vacation in hawaii, etc.

so although our vertical infection rate looks like its peaked, each one of these lateral infections can generate more vertical growth.

so unless we get very lucky, we are going to need a vaccine or at least a breakthrough treatment cocktail to put this behind us.

https://www.cbsnews.com/news/coronav...drug-testing/#


San Diego lab claims to have discovered a coronavirus vaccine in 3 hours — but testing it will take months




Researchers at a San Diego lab say it took them just three hours to come up with an experimental vaccine for the coronavirus — a potential weapon against the illness which has infected tens of thousands of peopleworldwide. Inovio Pharmaceuticals is now scrambling to test the vaccine, first in animals and then in people, and if it succeeds they hope to get it to the public as soon as possible, CBS San Diego affiliate KFMB-TV reports.

Chinese scientists released the genetic sequence for the coronavirus on January 9, and researchers at Inovio and other labs around the world immediately got to work.

"We have an algorithm which we designed, and we put the DNA sequence into our algorithm and came up with the vaccine in that short amount of time," Dr. Trevor Smith, Inovio's director of research and development, told KFMB.

"It's something we are trained to do, and the infrastructure is here and the expertise is in house," Smith said. The company has also worked on vaccines for Zika virus, Middle East Respiratory Syndrome (MERS) and Ebola.

Scientists hope the vaccine will work like a piece of biological software, according to KFMB — giving the human body instructions to launch a targeted attack in the form of T-cells and antibodies against the virus.

"I think it's every promising, and Inovio has very advanced technology that they're using with making a DNA vaccine, which is different than our traditional vaccines," Dr. Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security, told CBS News.

So far, KFMB reports Inovio's coronavirus vaccine has been tested on mice and guinea pigs. A clinical trial in humans could come next, perhaps by early this summer — which the company describes as record time. The scientists say they feel a sense of urgency to get an effective vaccine to the public. But even if all the testing proves successful, it would still take time to meet federal regulatory requirements and gear up for manufacturing.

The lead researcher of the company is at the World Health Organization (WHO) in Sweden, working on a plan of attack against coronavirus.

On Tuesday, WHO Director-General Dr. Tedros Adhanom Ghebreyesus said there is currently no vaccine or proven therapeutics to treat coronavirus, but global experts are collaborating to help stop the spread of the deadly virus, using a blueprint developed after the West African Ebola outbreak.

"We activated the R&D Blueprint team in early January to coordinate and facilitate information-sharing on research elements of the response," Ghebreyesus said at the research and innovation forum on the virus earlier this week.

In addition to Inovio Pharmaceuticals, HealthDay reports"possibly dozens" of other labs are also hard at work on finding a vaccine. A Massachusetts biotech company called Moderna is working on a version with the National Institutes of Health and hopes to start safety testing in April, the Washington Post reports.

But while the process is moving with remarkable speed, experts say patience is still required.

"Even though we are seeing rapid vaccine development with this virus, vaccine development is usually seen on the scale of years, not months," Dr. Adalja said.

"We will likely see rapid initiation of clinical trials that will establish the safety and then establish that [the vaccine] is actually creating immunity, and then figure out the dose of the vaccine... You need all of that to be figured out."

If the Inovio vaccine or another lab's version is successful, Adalja thinks it would still take "about a year" for it to become available to the public.

"It's one thing to make a vaccine that actually works, but you also have to manufacture it in sufficient quantities for it immunize the population that it's indicated for, and you have to be able to have that whole manufacturing process done in an appropriate manner so you can make these [vaccines] safely and quickly and according to good manufacturing practices. All of that takes time," he explained.

So far, at least 1,370 people worldwide have died from the coronavirus, which the World Health Organization has now named COVID-19. Almost all of the cases have been in China, where the outbreak originated.

Fifteen cases have been confirmed in the U.S. as of February 13 — mostly in people who had recently traveled to Wuhan, China.

Symptoms of the coronavirus include fever, cough and shortness of breath, according to the CDC. Some patients only show mild symptoms and recover, but others have developed life-threatening complications like pneumonia. The CDC says symptoms can appear in as few as two days or as long as 14 days after initial exposure.

[Sanlmar]

And I thought the purpose of this thread was to share ideas on how best to profit from this crisis from the safety of our respective hermetically sealed bunkers.

So you want to be dealt in?

Here’s one

Macau casinos were scheduled to reopen Feb 20th after a 2 week closure.

Red or black?

[MumblesBadly]

And I thought the purpose of this thread was to share ideas on how best to profit from this crisis from the safety of our respective hermetically sealed bunkers.

So you want to be dealt in?

Here’s one

Macau casinos were scheduled to reopen Feb 20th after a 2 week closure.

Red or black?

Not a great fan of trying to guess fin market movements on publicly traded stocks when I don’t have an informational advantage over better informed investors/traders. Prepper consumer goods to resell after the panic intensifies could, however, be more predictably profitable.

[sonatine]

so we are seeing a phase change in the infection model, according to available data.

total daily infections are down, but the overwhelming majority of those new infections were in quarantined burn zones in china, so its possible that telling everyone to stay in their homes and not touch anything ever and if they die they die, is having the desired effect.

unfortunately what we are seeing are 'embers' popping up everywhere. isolated incidents of new infections among people who were suspect but cleared are happening. one in europe, another who just got back from a vacation in hawaii, etc.

so although our vertical infection rate looks like its peaked, each one of these lateral infections can generate more vertical growth.

so unless we get very lucky, we are going to need a vaccine or at least a breakthrough treatment cocktail to put this behind us.

https://www.cbsnews.com/news/coronav...drug-testing/#


San Diego lab claims to have discovered a coronavirus vaccine in 3 hours — but testing it will take months




Researchers at a San Diego lab say it took them just three hours to come up with an experimental vaccine for the coronavirus — a potential weapon against the illness which has infected tens of thousands of peopleworldwide. Inovio Pharmaceuticals is now scrambling to test the vaccine, first in animals and then in people, and if it succeeds they hope to get it to the public as soon as possible, CBS San Diego affiliate KFMB-TV reports.

Chinese scientists released the genetic sequence for the coronavirus on January 9, and researchers at Inovio and other labs around the world immediately got to work.

"We have an algorithm which we designed, and we put the DNA sequence into our algorithm and came up with the vaccine in that short amount of time," Dr. Trevor Smith, Inovio's director of research and development, told KFMB.

"It's something we are trained to do, and the infrastructure is here and the expertise is in house," Smith said. The company has also worked on vaccines for Zika virus, Middle East Respiratory Syndrome (MERS) and Ebola.

Scientists hope the vaccine will work like a piece of biological software, according to KFMB — giving the human body instructions to launch a targeted attack in the form of T-cells and antibodies against the virus.

"I think it's every promising, and Inovio has very advanced technology that they're using with making a DNA vaccine, which is different than our traditional vaccines," Dr. Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security, told CBS News.

So far, KFMB reports Inovio's coronavirus vaccine has been tested on mice and guinea pigs. A clinical trial in humans could come next, perhaps by early this summer — which the company describes as record time. The scientists say they feel a sense of urgency to get an effective vaccine to the public. But even if all the testing proves successful, it would still take time to meet federal regulatory requirements and gear up for manufacturing.

The lead researcher of the company is at the World Health Organization (WHO) in Sweden, working on a plan of attack against coronavirus.

On Tuesday, WHO Director-General Dr. Tedros Adhanom Ghebreyesus said there is currently no vaccine or proven therapeutics to treat coronavirus, but global experts are collaborating to help stop the spread of the deadly virus, using a blueprint developed after the West African Ebola outbreak.

"We activated the R&D Blueprint team in early January to coordinate and facilitate information-sharing on research elements of the response," Ghebreyesus said at the research and innovation forum on the virus earlier this week.

In addition to Inovio Pharmaceuticals, HealthDay reports"possibly dozens" of other labs are also hard at work on finding a vaccine. A Massachusetts biotech company called Moderna is working on a version with the National Institutes of Health and hopes to start safety testing in April, the Washington Post reports.

But while the process is moving with remarkable speed, experts say patience is still required.

"Even though we are seeing rapid vaccine development with this virus, vaccine development is usually seen on the scale of years, not months," Dr. Adalja said.

"We will likely see rapid initiation of clinical trials that will establish the safety and then establish that [the vaccine] is actually creating immunity, and then figure out the dose of the vaccine... You need all of that to be figured out."

If the Inovio vaccine or another lab's version is successful, Adalja thinks it would still take "about a year" for it to become available to the public.

"It's one thing to make a vaccine that actually works, but you also have to manufacture it in sufficient quantities for it immunize the population that it's indicated for, and you have to be able to have that whole manufacturing process done in an appropriate manner so you can make these [vaccines] safely and quickly and according to good manufacturing practices. All of that takes time," he explained.

So far, at least 1,370 people worldwide have died from the coronavirus, which the World Health Organization has now named COVID-19. Almost all of the cases have been in China, where the outbreak originated.

Fifteen cases have been confirmed in the U.S. as of February 13 — mostly in people who had recently traveled to Wuhan, China.

Symptoms of the coronavirus include fever, cough and shortness of breath, according to the CDC. Some patients only show mild symptoms and recover, but others have developed life-threatening complications like pneumonia. The CDC says symptoms can appear in as few as two days or as long as 14 days after initial exposure.

is it possible that a san diego biotech firm trading at $2 a share had the resources to engineer a viable vaccine in days, where the cumulative resources of the 2nd largest economy in the world failed?

sure.

but if i dump a bunch of bleach into a syringe and inject it into an infected mouse, i might also be legally entitled to say i used a proprietary algorithm to engineer a viable vaccine in days.

[sonatine]

1st confirmed case in africa.

[gauchojake]

As someone in the medical industry who has seen this before, my suggestion for everyone is that once this has subsided, you go and buy a box or two of N95 masks. Stash them in your bag.

Want to hear something crazy? Cardinal Health had a massive recall on PPE (surgical gowns) at the same time this thing was getting started. Conspiracy theorists...go

[OSA]

1st confirmed case in africa.

I wonder what ABDULLAH AMDALLAH has to say about this

[Gordman]

1st confirmed case in africa.

I wonder what ABDULLAH AMDALLAH has to say about this

WAT?

[Dan Druff]

Great... the vaccine will be ready just in time for WSOP.

Funny how these things always work themselves out.

[Sanlmar]

Great... the vaccine will be ready just in time for WSOP.

Funny how these things always work themselves out.

Is the only known occurrence of chips being washed on planet earth the WSOP chips? Maybe they are just new....

I have heard they don’t stick together like ROW.

What’s it like Druff?

[sonatine]

https://www.caixinglobal.com/2020-02...101516740.html


3000+ medical workers have become infected.

50% of critical infections die.

[dwai]

https://www.caixinglobal.com/2020-02...101516740.html


3000+ medical workers have become infected.

50% of critical infections die.

must not be too many "critical infections"

[splitthis]

How many cities are they gonna drop these corona monsters in jus lol.